Physiological Transport Forces Govern Drug Distribution for Stent-Based Delivery
نویسندگان
چکیده
منابع مشابه
Physiological transport forces govern drug distribution for stent-based delivery.
BACKGROUND The first compounds considered for stent-based delivery, such as heparin, were chosen on the basis of promising tissue culture and animal experiments, and yet they have failed to stop restenosis clinically. More recent compounds, such as paclitaxel, are of a different sort, being hydrophobic in nature, and their effects after local release seem far more profound. This dichotomy raise...
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ژورنال
عنوان ژورنال: Circulation
سال: 2001
ISSN: 0009-7322,1524-4539
DOI: 10.1161/hc3101.092214